Over the past 20 years, a simple narrative has emerged about cannabis: CBD is the medicine in medical marijuana, now available in 34 states, and THC is the intoxicant in adult-use marijuana that’s legal in 10 states. Two different compounds; two different markets.
That narrative, along with the groundswell of belief in the curative properties of CBD (cannabidiol) as it’s being added to every sort of food, beverage, cream, potion, and lotion, drove more than $600 million in sales in 2018. And according to an analysis by the Brightfield Group, the CBD market is projected to grow to $22 billion by 2022 -- a number fueled by the recent federal legalization of hemp, from which cannabinoid can be derived. Reinforcing the cannabis duality, under the new law all things CBD must essentially be free of THC (tetrahydrocannabinol); hemp cannot exceed 0.3 percent of the psychoactive compound.
But new research is throwing a giant curveball at all this. Published in the journal Scientific Reports, the study analyzed data from more than 3,300 medical marijuana patients who used an app called Releaf to track how various products -- flower, tinctures, edibles, etc. -- affected their symptoms. Over 21 months, every time subjects consumed a product, they recorded the ratio of THC to CBD listed on the label, and the relief in their symptoms, which ranged from anxiety and depression to chronic pain and seizures.
The researchers found that among nearly 20,000 sessions recorded by patients, the average improvement of symptoms was 3.5 points on an 11-point scale that went from zero (not detectable) to 10 (severe). But the zinger was this: The higher the THC level, the more relief the patients got -- which was not true of CBD. “In our study, CBD appeared to have little effect at all,” says coauthor Jacob Miguel Vigil, Ph.D., associate professor in the department of psychology at the University of New Mexico. “But THC generated measurable improvements.”
Sarah See Stith, Ph.D., another coauthor and assistant professor in the department of economics at the university, suggests the results could be due to the fact that the app measures immediate symptom relief, while CBD has a more subtle, long-term effect. Or, perhaps, the THC needs a threshold amount of CBD to have a benefit. “We just don’t know, but when you compare flower and concentrates, the THC is what jumps out as having an effect,” she says. “And that goes against the common dogma.”
The study also challenges the wisdom of isolating CBD, an already booming industry anticipating runaway growth since the legalization of hemp. Patients reported the best results from smoking or vaping dried whole flower (usually the least expensive cannabis product available). “Reformulation makes business sense,” says Franco Brockelman, cofounder and CEO of Releaf, “but if you think about nature and plants, there is a lot of inherent natural design in cannabis, and it’s a bit of hubris to think at this point you can improve on that by dissecting it. There is a lot to be said for whole-plant medicine and using it that way.”
Brockelman got the idea for the app in 2014 when his mother agreed to explore legal medical marijuana after many years of failed conventional treatments for her psoriatic arthritis. She’d never smoked or been a drinker and received a Massachusetts medical marijuana card that allowed her access to a dispensary. But there was no guidance for selecting an effective product, which made the whole process daunting.
Brockelman decided to create a company that would assist people like his mother. He realized, he says, that “if we could provide patients with a good journal, they could help themselves, and we could look at that aggregate data to help dispensaries to know more about their products.”
Releaf has made its data available in anonymous form to the University of New Mexico researchers for ongoing studies. Vigil argues that the findings they’ve already published make a compelling case for federally legalizing THC. “It is curious that THC is still the single chemical that is illegal and not available for research,” he says, “and yet it’s got the most therapeutic potential.” Of course, this research is just one study on a subject that notoriously lacks strong research. But if the findings are right, they could widely reshape the green industry going forward.
Thanks to: https://www.greenentrepreneur.com
by Richard Holt
With vast numbers of people taking addictive and hazardous prescription painkillers, more investment needs to be made into natural, cannabis-derived alternatives like CBD.
Anyone who has suffered from chronic pain will know that the effect on your life can be extremely corrosive.
Next time you see someone walking down the street looking miserable, consider this: maybe back pain kept them awake all night, and now that same pain has formed a pincer-movement with the tiredness, making it extremely difficult not to look like a grumpy sod.
Lots of people are in pain, and there are many potential remedies, both under and over the counter, inside and outside of the law.
Let us consider two: opiates and cannabis.
Opiates include drugs like tramadol and oxycodone – semi-synthesised, opium-derived drugs in the same group as heroin. They are highly addictive, can kill you if you take too much, and yet are prescribed by doctors to hundreds of millions of people around the world.
Cannabis is a plant that has been used effectively for thousands of years, causes no physical dependency, and has never been shown to cause a single fatality. The downside is that in most of the world, including the UK, using it makes you a criminal.
There is, however, an alternative that is legal – at least for now. Cannabidiol, or CBD, is a compound that is found in cannabis and hemp plants. It does not contain any of the psychoactive part of cannabis – the THC – so it does not get you ‘high’.
But CBD oil has been found by many people to be effective at reducing pain and inflammation, as well as tackling insomnia.
A recent study suggested that there were 250,000 users in the UK alone. It has become particularly popular among sportsmen because of the effect it has on recovery.
Trent Scanlen founded truthnaturals.co.uk, a company selling CBD oil, after finding that it helped during his recovery from cancer.
‘I used CBD through my cancer treatment as it helped me sleep, made me less anxious and also allowed me to reduce the cocktail of drugs that I was on. I talked to one of my doctors about it and he said that lots of his patients used it and got great results but at the time it was illegal so he wasn’t allowed to prescribe it.’
Since 2016, CBD has been classed as a medicine in the UK and there have been a few cases where it has been prescribed on the NHS. Earlier this year 11-year-old Billy Caldwell, who suffers from severe epilepsy, saw an ‘incredible’ reduction in the number of seizures he was suffering.
He had originally been given CBD by doctors in the US, but when he returned home to Northern Ireland his GP continued the prescription.
There is also some limited use of CBD on the NHS to treat multiple sclerosis.
But such cases are very rare – doctors will only ever prescribe it in exceptional cases until there is significant investment into clinical trials to demonstrate its effectiveness.
Drugs expert Dr Henry Fisher, policy director from the medical think-tank Volteface, said: ‘There are millions of people in the UK currently experiencing chronic pain, for which the main pharmaceutical treatments on offer are either anti-inflammatory drugs, gabapentinoids or opioids.
‘By excluding cannabis-derived medicines from the doctor’s toolbox, access to some of the most effective options for pain relief is being prevented.
‘Side effects from chronic use of opioids and other pain medication can be severe, and not everyone responds positively to the same treatments, which is why having more options available for doctors to prescribe is hugely important.‘
Money is being put into research – Oxford University, for example, has announced a £10million programme to test all of the compounds in cannabis – but the scale is limited. The Government still describes cannabis as a ‘harmful drug’ and this stance seems to have set it against the use of anything associated with cannabis, even compounds like CBD with no psychoactive effects.
A lot of the reluctance to put the necessary investment into cannabis-derived products stems from outdated views on drugs.
Thanks to: http://awakeandaware.ca
Medical Cannabis is Healing Autism
Medical Cannabis is Healing Autism
Medical Cannabis is Healing Autism – autism spectrum, also known as autistic spectrum, autism spectrum, autism or the Short Name, is sequencing syndromes that have a clear common denominator with classic autism. All syndromes are called jargon too pervasive developmental disorder.
In the past, the spectrum was divided L”aotizm Classic “and various phenomena mentioned it, but now classic autism and some of those symptoms are considered L”aotizm”, while another part of the phenomena is not considered more autism. DSM before, called the DSM-IV generalized spectrum, alongside autism classic the Asperger Syndrome and disturbing the social Pervasive Developmental not associated with (PDD-NOS) “, as alongside
Tourette’s syndrome and childhood disintegrative disorder (CDD), despite Ssiicotn spectrum was less obvious .
Autism is not a specific disease are a number of symptoms diagnosed on the autistic spectrum. There are some doctors diagnosed ADHD syndrome Asfbrgr part of the spectrum Haotisti.aotizm overall situation is characterized by many: lack of social competence, communication difficulties and repetitive behaviors and introverted.
Medical Cannabis is Healing Autism – some types of autism are considered to be the product of a lack of protein (or too low amount) Ando Knboaidi type are naturally in our bodies and they are their equivalent plant world are the T Hitz C. and CIA me enough. This is true for a few more dances that are not related to autism. Many research institutions in place because of the relationship between material Hknboaidi we have in our body to that medical cannabis is likely to effectively treat autism resulting from this can be compensated in treating medical cannabis.
Medical Cannabis is Healing Autism -btifol through many donations of medical cannabis symptoms of autism are considered less desirable, for example: self-injury, destruction of property, panic attacks, aggression and tantrums.
A study done in 2013 on the effects of the system Hanknboaidit autism found many effects at the level of neurons leads to a reduction in behaviors unwanted described examinee. The study relies on a second study in the same year and studied the effects on different areas of the brain of the active ingredients of cannabis and how they impact positively on candidates with autism.
Medical Cannabis is Healing Autism – US research team found in 2013 the relationship between medical cannabis active ingredients for the bodies of children who are dealing with autism. Because of the known relationship between the immune system active substances of medical cannabis and the relationship of the immune system appears autism in children Ask the authors examine whether strengthening the immune system of a child is able to curb the phenomenon of autism in children diagnosed with levels Knboaidim lower body and brain (mostly). the study was done at the Department of Pharmacology at the university of Nepal described autism as a disorder neurological developmental induced genetic reasons and environmental issues that affect the body. the team explains shown autism as a lack of regulation and immune system cells in our blood Had behaving differently in children who are dealing with autism.
The researchers took a group of children who are dealing with autism and a group of children “healthy” and compared the CB2 protein count in the group with autism to that of the group “Creation” using medical marijuana.
Set investigating team would be expected due to the increase in protein associated with the regulation of this behavior can be viewed at the moment with autism and relieving treatment.
Medical Cannabis is Healing Autism – there are many studies that focus on the medicinal properties of medical cannabis in the treatment of autism. Many studies have focused on protein activity and CB2 receptors CB1 known as the effect of these proteins to the immune system and cellular activity of cells in the body.
Medical Cannabis is Healing Autism – the stories of children who struggle with autism and use medical marijuana stands out a whole story Sam boy of eight from the United States and how medical marijuana has improved his life. Lifestyle of Sam and particularly unwanted behaviors such as screaming, kicking and spitting measured to understand the change in future medical cannabis make the life of Sam. the experiment that started in 2008 brought to an end following conclusions about the life of Sam after treatment of autism with whom he deals using medical marijuana and the conclusions are: medical cannabis took a significant amount unwanted behaviors and helped Sam to raise quality his life. Sam’s parents testified that Sam seems happier before medical cannabis therapy and noted the following improvements in the three categories of great improvement, improvement of medium and little improvement.
A big improvement Sam’s parents documented: a significant decline in tears for no reason, a significant decrease in anxiety attacks, a significant drop lack of cooperation.
Moderate improvement Sam’s parents found improvement in the way Sam share this he is happy, improvement in dealing with sudden ions schedule and more.
Improving Moat- recorded Sam’s parents: better learning abilities, better social behavior towards classmates and others.
Sam’s case the trial was stopped after six years in 2014 after the parents of Sam and all the surroundings have been convinced long ago the plant’s medicinal properties of cannabis and how they helped Sam to flourish. Today Sam medical cannabis use between 4 to 6 times a week, especially in the late afternoon. Bassam treatment using medical cannabis during these six years, Sam helped build social relationships and grow a happy boy who suffers fewer unpleasant symptoms that accompany autism.
As can be seen from the case of Sam medical cannabis treatment has improved the quality of his life and his parents and helped them:
Medical Cannabis is Healing Autism – conclusion can review the information we provide and see that medical effect can be affections so much with autism, through the merits of medical marijuana and its active ingredients we can
cope with autism. Most studies have focused on receptors CB1 and CB2, the protein due to impact much on the body and in this case the immune system and the body’s nervous directly related to autism. We have also seen how the studies support the use of cannabis to treat autism or rather treat symptoms, especially unwanted behavioral autism appear. Medical cannabis has been shown to decrease aggression and anxiety in autistic and affects different social behaviors for the better.
Thanks to: https://en.thcendcbd.com
Crohn’s disease is a type of intestinal inflammation issue that is likely caused by the immune system essentially attacking otherwise harmless bacteria or food causing inflammation in the gut and bowels. It causes great pain and discomfort and often times surgery is needed to remove pieces of the intestines that are too badly inflamed to heal.
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To many doctors, this is considered a mystery illness; as there is no known cause and some doctors believe it is an autoimmune disease. Luckily, new research has shown how cannabis has provided a complete remission from this disease for those participants who were involved in this study.The study, which was conducted in October 2013 and was published in the journal, Clinical Gastroenterology and Hepatology, involved the use of the effects of the marijuana plant aka Cannabis Sativa, had on patients’ and their symptoms of Crohn’s disease and Irritable Bowel Disorder (IBD.) It included 21 patients (13 men and 8 women) suffering from Crohn’s disease and other IBD’s in a controlled setting. The average age of the participants was 40-years-old. Every single person involved in this study had previously tried treating their disorder with steroidal therapy, immunomodulators or anti-tumor agents with no luck.The researchers split the patients into two groups, eleven of them were given rolled cannabis to smoke that contained 115 mg of THC, two times daily. The remaining group acting as the placebo group were also given rolled cannabis to smoke, only this time it contained no THC.
The Findings Were As Follows,
By the end of the study, the researchers found:
Despite the promising research, researchers are still questioning whether the effects of cannabis on symptoms of Crohn’s disease and Crohn’s flareups are actually masking the root cause of the issue, which is still considered a mystery. Cannabis appears to be an effective method of treatment because it has been found that those suffering from Crohn’s actually produce fewer endocannabinoids, which is the body’s natural THC production. This is why providing cannabinoids for the receptors that are naturally in your body can help to combat inflammation that is caused by Crohn’s or IBD.
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Is Marijuana A Viable Treatment For Crohn’s Disease?
At the very least, the research that was conducted shows how it is definitely worth a shot, a potential cure with no side effects? Really, there is nothing to lose by just trying it out and seeing if it works for you. It’s a very simple method that could provide life-changing benefits.There are a few action steps that should be taken if you are looking to consider this as an option for yourself…1. Make an appointment with your doctor to assess your symptoms, mention this article or the study that shows how cannabis can be a potential treatment option.2. If medical marijuana is legal in your state and your doctor agrees that it could be a potential cure, then continue with a prescription for medical marijuana.3. Some medical marijuana dispensaries will provide you with a card if you already have a prescription for painkillers or something similar, or if you tell them that you are in pain and need something to help. This would be a last resort option if you were unable to get a prescription from the doctor.
What If You Don’t Have Access To Medical Marijuana?
Move. Just kidding. Ultimately, this disease is related to the diet in some sense. Author of the hugely successful book, Medical Medium, Anthony William has provided some amazing tools and resources in his book, online blog posts and in the form of podcasts where he shares the foods that are triggers and which should be avoided at all costs, foods that heal, restore and repair our gut and entire digestive system, and herbal supplements to offer support.
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Thousands of people have had success from following the Medical Medium’s protocol, I highly suggest the aforementioned book above for healing. Realistically, diet is the most important part of true healing here, and although cannabis is a viable option for treating symptoms, it is important to really get to the root cause of the issue and heal the issues that are causing this problem in the first place.Don’t forget – all illness’ manifest in order to show you something. Maybe something in your life is not working for you, maybe your diet needs to change, maybe you, yourself are in need of a big change. If you try to see the illness as an opportunity to stop, see what’s not working and truly heal instead of resisting it, despite the fact that it may be very painful and difficult, the whole process may become easier for you. Don’t forget, mystery illness or not, our bodies are perfectly capable of healing themselves if given the right environment.
Thanks to: http://www.collective-evolution.com
by Mary Biles, November 6th, 2017
I’m no doctor, but I thought I was familiar with the key biological systems in the body. Turns out though, I was wrong. That’s because unless you’re a research scientist or work in the field of medical cannabis, it’s unlikely you’ll ever have been told about the endocannabinoid system. And yet, it has been hailed as “the most important physiologic system involved in establishing and maintaining human health.”
Why do so few people know about the endocannabinoid system?
So what’s the big mystery? Well, it might have something to do with how the endocannabinoid system (ECS) was discovered. Back in the 1990s scientists were trying to understand how THC, the psychoactive substance in the cannabis plant, elicits its effect on the body. What they uncovered was a complex network of receptors (CB1) in the brain and central nervous system that were a perfect fit for the THC molecule.
Soon after another type of receptor (CB2) was discovered in the immune system, gut and many of the body’s major organs. But that was only part of the puzzle. The hunt was on to find out whether the body produced its own cannabis-like chemicals, and with the identification of the first endocannabinoid Anandamide, they had their answer.
What does the endocannabinoid system do?
What scientists have realised is that the endocannabinoid system fine-tunes most of our vital physiological functions, bringing balance to everything from sleep, appetite, pain, inflammation, memory, mood and even reproduction. So in basic terms, it’s like a conductor of an orchestra, ensuring that no one section is drowning out the other, with the end result a perfectly harmonised symphony between body and mind.
Sounds like pretty important work, right? Well, you’d be right. That’s why it’s vital that the ECS becomes as much part of everyday parlance as the immune system. So to get the ball rolling, here are 8 fascinating facts about the totally awesome endocannabinoid system.
1. Humans aren’t alone in having an ECS
As humans beings we’re not special for having an ECS. Not only is the endocannabinoid system found in all vertebrates, but scientists also discovered cannabinoid receptors in non-vertebrate sea-squirts, suggesting an evolutionary process dating back 600 million years ago.
2. CB1 receptors are the most abundant neurotransmitter receptors in the brain
Most of us have heard of neurotransmitters – they’re the chemicals that communicate information throughout the brain and body. Serotonin and dopamine are perhaps the most well known examples, but it’s the endocannabinoid Anandamide, also classed as a neurotransmitter, that has the most receptors in the brain.
3. Endocannabinoids signal backwards
Most neurotransmitters communicate in one direction: from the signaling neuron to the postsynoptic neuron. But in the endocannabinoid system, it works in the opposite direction, which is called retrograde signaling. This means that if a receptor is being over- or under-stimulated, it signals backwards across the synapse telling the signaling neuron to change its behaviour, creating a kind of feedback loop. So in effect, rather than distributing information like other neurotransmitters, it acts like a kind of dimmer switch, turning activity up or down in order to return the body to homeostasis.
4. Increased endocannabinoid system activity has been noted in many diseases
As the endocannabinoid system’s modus operandi is to bring balance to the body, it’s no surprise then that scientists have observed elevated ECS activity in a number of illnesses. Everything from neurodegenerative diseases such as Alzheimer’s and Parkinson’s, to rheumatoid arthritis and cancer, have shown changes in endocannabinoid levels and greater receptor expression. The conclusion that has been most widely reached is that this increased activity denotes the ECS trying to fulfil its role of returning the body to equilibrium again.
5. ‘Endocannabinoid System Deficiency’ may be a cause of some illnesses
But what happens if the ECS becomes depleted? Scientists have observed how in certain conditions associated with oversensitivity to pain such as migraines, fibromyalgia and IBS, the ECS appears to have become weakened. The theory is known as Clinical Endocannabinoid Deficiency, with the corollary being that by supplementing the body with compounds from the cannabis plant, this deficiency can be corrected and the symptoms improved.
6. The ECS explains why medicinal cannabis has a therapeutic effect
Prior to 20th century prohibition, cannabis had been used for thousands of years to treat a whole host of ailments from epilepsy, headaches, arthritis, pain, depression and nausea. Back then nobody knew why the plant showed such therapeutic versatility. The discovery of the endocannabinoid system soon shone new light onto the medicinal effects of cannabis. Sadly, this has coincided with a time when the vast majority of the population have been precluded from accessing it.
According to Dustin Sulak, a leading medical cannabis expert:
“Research has shown that small doses of cannabinoids from cannabis can signal the body to make more endocannabinoids and build more cannabinoid receptors… I believe that small, regular doses of cannabis might act as a tonic to our most central physiologic healing system.”
7. You don’t have to break the law to give your endocannabinoid system a boost
Currently, medical cannabis-friendly countries are in the minority across the planet. So what can you do if can’t legally access the plant? Well, you could consider trying CBD, a non-psychoactive compound in the cannabis plant, that has a whole host of health benefits such as reducing inflammation, calming feelings of anxiety, and even lowering the frequency of epileptic seizures. CBD is normally extracted from cannabis plants with less than 0.2% THC, commonly referred to as hemp or industrial hemp, allowing it to be bought legally in most countries worldwide.
Another option is to peel yourself off the sofa and get moving. Scientists have found that prolonged aerobic exercise increases levels of the feel-good endocannabinoid, Anandamide.
Diet is also a useful target. Increasing Omega 3 found in oily fish or healthy seeds like flax or hemp, can help support endocannabinoid brain signalling. Leafy green vegetables are also thought to stimulate the ECS as they contain beta-caryophyllene which activates the CB2 receptor.
8. Most doctors know very little about the endocannabinoid system
With the ECS playing such a central role in our health, you would think that any self respecting member of the medical profession would have some knowledge of its existence. But in mainstream medicine, the endocannabinoid system remains rather a pariah.
In 2013 a survey was conducted asking medical school in the United States whether the ECS formed part of their curriculum. The authors found that only “13% teach the endocannabinoid system to future doctors.”
A lot can change in four years, and while in some European countries such as the UK and Spain the ECS does make it onto some medical school syllabuses, it cannot be denied that the majority of professionals in charge of our healthcare remain very much in the dark.
So now you’re endocannabinoid savvy, there’s no turning back. Join me and start spreading the word to all that will listen. It’s time that the ECS is given the attention it deserves both by our healthcare providers and the public at large. If like me you feel moved to take action, why not start by speaking to your doctor? Have they heard of the endocannabinoid system? You never know, perhaps you are the very person to inform them.
“The Centers for Disease Control (CDC) in Atlanta declares that 33% of the babies born this year will be diabetic by the year 2050. – Dr. Alan Cantwell”
Cannabidiol and Magnesium Help Treats Diabetes
With permission from
Dr. Eddy Bettermann MD
July 28, 2018
There is nothing more needed in medicine today than a way of treating diabetes and metabolic syndrome because these syndromes lead directly to cancer, heart disease and stroke. I wrote New Paradigms in Diabetic Care to address what doctors and medical officials are loath to face—the real causes of diabetes. Diabetes is not the hopeless disease that most doctors would have us believe. There are safe treatments and lifestyle changes that will prevent diabetes from destroying your life.
The Centers for Disease Control (CDC) in Atlanta declares that 33% of the babies born this year will be diabetic by the year 2050. – Dr. Alan Cantwell
When we find out that diabetes and metabolic syndrome are caused by toxic insults from heavy metals, radiation exposure and chemicals running smack into major nutritional deficiencies, we begin to stumble upon treatment pathways that actually work. Diabetes is actually an extremely serious warning to civilization; it is an announcement that the rising tide of radiation, mercury, other deadly chemicals and pharmaceutical drugs are poisoning humanity. The cost of not treating diabetes in a truly effective way is steep. Diabetes can contribute to, among other things, eye disorders and blindness, kidney failure, amputation, nerve damage, heart disease and stroke. Diabetes makes pregnancy more difficult and can cause birth defects.
Populations are being simultaneously poisoned and starved by the food they eat.
Dangerous or Safe Approaches to Diabetes
What we are introducing in this chapter is a pair of medicinals that will positively impact diabetic treatment. Magnesium chloride and cannabinoid medicine together shame contemporary medicine’s shockingly dangerous approach, which cures no one. “Conventional drug treatment for diabetes does not have a good track record. Prescription drugs have various side effects and are associated with severe health complications. Several researchers have revealed that long-term use of some common diabetes drugs can increase the risk of cancer and heart disease. An analysis of five-year data collected from an ongoing 10-year study, conducted by Takeda Pharmaceuticals, showed a link between the common anti-diabetes drug Actos and increased risk of bladder cancer”, writes Dr. Marc Ott.
80% of patients use 2 or more diabetes drugs every day.
The Food and Drug Administration (FDA) requires oral diabetes medicines to carry a warning regarding increased risk of heart attack. Medications for type-2 diabetes actually do more harm than good. In February 2008, researchers heading a large, government-funded trial made a sobering announcement. The Action to Control Cardiovascular Risk in Diabetes (ACCORD) study, designed to evaluate the effectiveness of various medication regimens, found that the most intensive drug regimens aimed at driving blood sugar way down resulted in a much higher cardiovascular death rate. Intensive blood-sugar-lowering treatment proved to be so harmful that the researchers halted the study 18 months early to prevent this aggressive drug use from killing even more people.
Avandia raises the risk of heart attacks and possibly deaths. Yet more than 6 million people worldwide have taken the drug to control blood sugar since it came on the market 12 years ago.
Medical science has known about the fatal complications of diabetes drugs since 1969 when results of a similar study called the University Group Diabetes Program were made public. That study also had to be stopped two years early because participants who were taking the drugs had a 250-300 percent higher death rate than those taking the placebo.
Dr Julian Whitaker says that, “The majority of patients with type-2 diabetes who come to the Whitaker Wellness Institute are taking at least one oral medication. We stop these drugs on sight. If they’re on insulin and they’re overweight, we stop the insulin as well. Giving insulin to heavy type-2 diabetics is a recipe for further weight gain and does more harm than good. As you might imagine, this is a new concept. Patients are conditioned to trust their doctors, who have convinced them of the absolute necessity of taking drugs to lower blood sugar. However, once they hear the truth about diabetes drugs, most of our patients opt to stop their medications and adopt a much healthier treatment approach targeted at lowering blood sugar and reducing risk of heart disease and other complications.”
Most pain and anti-inflammatory medications are not safe; even the over–the-counter pain medications hold unforeseen dangers. Despite more than a decade’s worth of research showing that taking too much acetaminophen can ruin the liver, the number of severe, unintentional poisonings from the drug is on the rise, a 2005 study reports. The drug, acetaminophen, is best known under the brand name Tylenol. Compounds containing Tylenol include Excedrin, Midol Teen Formula, Theraflu, Alka-Seltzer Plus Cold Medicine, NyQuil Cold and Flu and Paracetamol as well as other over-the-counter drugs and many prescription narcotics, like Vicodin and Percocet.
Inflammation, Magnesium and Diabetes
Inflammation plays a key role in a set of disorders that include type-2 diabetes, obesity, and heart disease—collectively called the metabolic syndrome (or Syndrome X). Dr. Steve Shoelson, a professor of medicine at Harvard Medical School has focused squarely on inflammation. Epidemiologists have found that patients with type-2 diabetes and cardiovascular disease have slightly elevated levels of inflammatory markers in their bloodstream.
Magnesium deficiency is pro-inflammatory. Magnesium deficiency induces insulin resistance, hypertension, dyslipidemia, endothelial activation and prothrombic changes in combination with the upregulation of markers of inflammation and oxidative stress. Though it is magnesium that modulates cellular events involved in inflammation, we can find another powerful and exceptionally safe medicine that can head inflammation off at the pass. When we understand the process of inflammation, and treat it with magnesium chloride, and other of my protocol items (Cannabinoids) we can put an end to a large amount of suffering.
Inflammatory reactions in the body are a valuable predictor of impending heart attack. Magnesium deficiency causes and underpins chronic inflammatory buildups. Magnesium deficiencies feed the fires of inflammation and pain. Increases in extracellular magnesium concentration cause a decrease in the inflammatory response. Magnesium literally puts the chill on inflammation especially when used transdermally.
Dr. Andrzej Mazur  said, “Magnesium deficiency induces a systemic stress response by activation of neuro endocrinological pathways. Magnesium deficiency contributes to an exaggerated response to immune stress and oxidative stress is the consequence of the inflammatory response.” Magnesium improves and helps correct insulin sensitivity, which is the fundamental defect that characterizes pre-diabetes, metabolic syndrome and even full blown diabetes and heart disease. An intracellular enzyme called tyrosine kinase requires magnesium to allow insulin to exert its blood-sugar-lowering effects. In several studies, daily oral magnesium supplementation substantially improved insulin sensitivity by 10% and reduced blood sugar by 37%.,
Let’s Not Forget the Sun. Researchers from Tuffs and Harvard are telling us that daily supplements of vitamin D boosts the function of the cells in the pancreas that produce insulin.
Medical Marijuana and Diabetes
Dr. Gregory T. Carter, Clinical Associate Professor of Rehabilitation Medicine, University of Washington School of Medicine says, “Marijuana is a complex substance containing over 60 different forms of cannabinoids, the active ingredients. Cannabinoids are now known to have the capacity for neuromodulation via direct, receptor-based mechanisms at numerous levels within the nervous system. These have therapeutic properties that may be applicable to the treatment of neurological disorders including anti-oxidative, neuroprotective, analgesic and anti-inflammatory actions, immunomodulation, modulation of glial cells and tumor growth regulation. Intracellular changes and altered signaling of the neurons seems to be the principle effects of the cannabinoids in marijuana.
Cannabinoids reduced inflammation in the brain and prevented cognitive decline. Cannabinoids have also been shown to alleviate neuropathic pain.
Marijuana has strong anti-inflammatory effects. “This is why I believe that people who used marijuana a few decades ago are much less likely to develop any disease, such as Alzheimer’s, that relies upon the slow development of brain inflammation,” said Dr. Gary Wenk. The recent discovery of an endogenous cannabinoid system with specific receptors and ligands (compounds that activate receptors and trigger their characteristic responses) has increased our understanding of the actions of marijuana. Excessive inflammatory responses can emerge as a potential danger for organisms’ health. Physiological balance between pro- and anti-inflammatory processes constitutes an important feature of responses against harmful events.
There is mounting evidence pointing to dysfunction of the endocannabinoid system having an important role in the development of type 2 diabetes and obesity. Insulin-induced glucose uptake increases with increasing THC concentration.
Professor Mike Cawthorne and the pharmaceutical giant GlaxoSmithKline believe that plant-based medicines might be the way to approach the treatment of diabetes. The particular plant they are studying is marijuana. Cannabis is an excellent anti-inflammatory that lacks the side effects of steroids, the NSAIDS, and the COX-2 inhibitors like Vioxx. This anti-inflammatory action may help quell the arterial inflammation common in diabetes.
Cannabidiol (CBD) arrested the onset of autoimmune diabetes in NOD mice in a 2007 study. Researchers at Hadassah University Hospital in Jerusalem  in 2006 reported that injections of 5 mg per day of CBD (10-20 injections) significantly reduced the prevalence of diabetes in mice from an incidence of 86 percent in non-treated controls to an incidence of only 30 percent. In a separate experiment, investigators reported that control mice all developed diabetes at a median of 17 weeks (range 15-20 weeks) while a majority (60 percent) of CBD-treated mice remained diabetes-free at 26 weeks. Investigators also reported that CBD significantly lowered plasma levels of the pro-inflammatory cykotines(proteins), INF-gamma and TNF-alpha, and significantly reduced the severity of insulitis compared to non-treated controls.
Cannabidiol – CBD – CBD also occurs in almost all strains and is the second most interesting cannabinoid in regards to medical cannabis. Unlike THC, CBD lacks noticeable psychoactive effects. Nevertheless, CBD has valuable medical properties. CBD appears to work synergistically with THC, bolstering its medical effects while moderating its psycho-activity. It is also thought to improve wakefulness and to enhance THC’s activity against pain. Taken by itself CBD has anti-inflammatory, antianxiety, anti-epileptic, sedative and neuro-protective actions. It is also a potent anti-oxidant, protecting against chemical damage due to oxidation. Studies have suggested that CBD could protect against the development of diabetes, certain kinds of cancer, rheumatoid arthritis, brain and nerve damage due to stroke, alcoholism, nausea, inflammatory bowel disease and Huntington’s disease.
Researchers concluded that confirmation of the observed immunomodulatory effects of CBD “may lead to the clinical application of this agent in the prevention of type-1 diabetes” and possibly other autoimmune diseases. They note that many patients diagnosed with type-1 diabetes have sufficient residual cells that produce insulin at the time of diagnosis, and may be candidates for immunomodulation therapy.
Bioactive cannabinoids have an anti-inflammatory effect. Marijuana can also be used to make topical creams to relieve neuropathic pain and tingling in hands and feet. Cannabis helps still diabetic “restless leg syndrome” (RLS), so the patient can sleep better: “It is recommended that patients use a vaporizer or smoke cannabis to aid in falling asleep.”
In studies THC essentially countered the effects of insulin resistance. These results support previous findings that smoking cannabis can reduce blood glucose in diabetics (Gallant, Odei-Addo, Frost, & Levendal, 2009).
Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. In current research on how to modulate cannabinoid receptors in the human body, Dr. Gregory I. Liou, a molecular biologist at the Medical College of Georgia, has found that cannabidiol (a cannabis compound) could prevent the overabundance of leaky eye blood vessels associated with diabetic retinopathy. As the leading cause of blindness in the United States, diabetic retinopathy is a major health concern for more than 16 million American adults.
Dr. Liou’s work, published in the January issue of the American Journal of Pathologyindicates that cannabidiol can interrupt the destructive points of action in diabetic animals. “What we believe cannabidiol does is go in here as an antioxidant to neutralize the toxic superoxides. Number two, it inhibits the self-destructive system and allows the self-produced endogenous cannabinoids to stay there longer by inhibiting the enzyme that destroys them.” Dr. Liou believes that cannabinoids act as a type of negotiator, trying to keep peace, harmony and balance between a host of potentially volatile and dangerous factions of cells. “Cannabinoids are trying to ease the situation on both sides.”
Cannabis is neuroprotective. It is believed that much of neuropathy comes from the inflammation of nerves caused by glycoproteins in the blood that deposit in peripheral tissues and trigger an immune response. Cannabis helps protect the nerve covering (myelin sheath) from inflammatory attack. Cannabis also lessens the pain of neuropathy by activating receptors in the body and brain. Some components of cannabis (perhaps cannibidiol) act as anti-spasmodic agents similar to the far more toxic anti-convulsants like Neurontin. This action of cannabis helps relieve diabetic muscle cramps and GI upset.
The Journal of the American College of Cardiology stated, “Collectively, our results strongly suggest that cannabidiol may have tremendous therapeutic potential in the treatment of diabetic cardiovascular and other complications.”
Dr. Mark Sircus AC., OMD, DM (P)
Thanks to Lou at: https://talesfromtheloublog.wordpress.com
By Susan Boskey
Cannabidiol (CBD) is everywhere today in health news. It has made cannabis respectable, once again. As one of over 100 chemical compounds in the cannabis plant and one that is non-psychoactive, CBD is a current stand-out in the cannabis family.
Of course, it wasn’t always this way. After 81 years of prohibition since the 1937 Marihuana Tax Act and the more recent 1970 Controlled Substance Act in the U.S., CBD has ushered in a renaissance of acceptance for the sacred plant (so-called in India). This, despite continued federal designation of cannabis as a “Schedule 1 drug” in the same category as heroin with criteria of: no accepted medical value, not safe for medical use, and highly addictive.
Starting at some point in the 1930s everything cannabis was lumped into the basket of “evil weed,” vilified for its psychoactive properties. Given the negative spotlight put on Black musicians and Hispanics in New Orleans and New York, it was considered a menace to white folk, and as seducing the young.  Panic over the plant was so palpable that cannabis as the medicine it always had been, didn’t stand a chance.
That was then and this is now. Evidence-based science is now showcased in the U.S. Government’s PubMed peer-reviewed publications, adding credibility to the many beneficial properties of and uses for CBD. First discovered in 1940 by an American chemist, Roger Adams, , the cannabidiol molecule was more fully understood when Israeli scientist, Rafael Mechoulam, isolated it in 1963. 
In a report of the February 2013 issue of The British Journal of Clinical Pharmacology CBD is cited as “an anti-inflammatory, anticonvulsant, anti-oxidant, anti-emetic, anxiolytic and antipsychotic agent, with the potential for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety and schizophrenia, respectively.”
The CBD molecule is also neuroprotective. It protects the brain from certain disease processes and degeneration while regulating neurotransmitter function. This benefit to the brain is what caught the attention of the government and, in 2003, led to their procuring U.S. Patent No. 6,630,507.
“It really puzzles me to see marijuana connected with narcotics dope and all of that stuff. It is a thousand times better than whiskey. It is an assistant and a friend.” ~Louis Armstrong, American musician, 1901-1971
CBD alters and lowers the overall psychoactive effect of THC, and is additionally considered a potential remedy for psychotic effects, and certain cognitive deficits such as PTSD and depression. Plus, it is documented to help with arthritis, diabetes, alcoholism, MS, chronic pain, antibiotic-resistant infections, and osteoporosis in women.
Thinking CBD is too good to be true? Think again.
The reason CBD (and other cannabis molecules) can help a number of different health conditions is because of its interface with the body’s endocannabinoid system (ECS). Every mammal has one. It is a signaling (communication) system that regulates the homeostasis (balance) of every physiological system of the body. However, due to toxic build-up in our bodies over time, the ECS can become deficient, lose effective functioning and lead to various disease processes.
CBD, when used as medicine, mimics many of the body’s naturally manufactured molecules vital in the interface with the ECS for optimal function. Because its external administration precisely mimics internally-made molecules, CBD can reduce potential ECS deficiencies that may be triggering physical and mental symptoms, and thereby restore efficacy of the ECS towards needed homeostasis.
The only problem is that many people now believe CBD is the good part of cannabis and THC is the bad part because of its psychoactive effects. This could not be further from the truth. Yet such thinking is easy to understand due to the stigma branded on cannabis, and also for the fact we have been conditioned by a more reductionist type of healthcare system – one drug for one organ or bodily system – to think of a remedy in isolation of its plant context.
Throughout ancient and modern history and until its prohibition, cannabis was valued holistically, both hemp and marijuana. Medicinally, the whole of the plant was used to ensure a synergistic and beneficial impact on a person’s overall, general condition beyond symptom management. Called the entourage effect, the interaction of the THC, CBD, and its other equally beneficial but less understood compounds, accounts for why the therapeutic use of cannabis provides relief to a wide variety of conditions.
Those of us helping others use cannabis as medicine are forever grateful to CBD for opening the door to the opportunity to provide deeper education about the whole cannabis plant and its genuine healing gifts.
Susan is a 2018 graduate of the Holistic Cannabis Academy with over 45 years of personal involvement in the spectrum of wellness modalities. Her mission today is to intervene in the noise of modern life and help people identify and remove stressors that trigger their dis-ease while providing strategies towards a living experience of inner calmness, contentment and inspiration.
Her curiosity about life, and health in particular, fueled her determination to learn everything she could and help others. Susan’s private practice (in-person and on Zoom) is based on the paradigm of whole-person wellness, body, mind and soul, and includes addressing lifestyle issues. As a non-physician coach she enjoys the added flexibility of providing in-depth care plans for her clients. Visit her website: http://lifestylewellnessrx.com
Thanks to: https://www.naturalblaze.com
Illinois Residents Can Now Swap Prescription Opioid Painkillers for Medical Marijuana
Illinois residents will now be able to seek out medical marijuana as an alternative to opioid painkillers through a new program allowing patients with prescriptions for opioids to instead opt for temporary access to the plant.
The Opioid Alternative Pilot Program was approved by the state legislature in an overwhelming vote last year of 44-6 by lawmakers hoping to curb a deadly epidemic of overdoses that claim over 100 lives per day.
In a statement, Illinois Department of Public Health spokesperson Melaney Arnold said:
“Along with the physician certification, a passport-like photo, copy of driver’s license/state ID, proof of Illinois address, and $10 payment is required … The OAPP offers individuals who have been or could be prescribed an opioid, another option for managing their pain.”
Under the program, anyone qualifying for a prescription for common opioids like Vicodin, OxyContin, or Percocet will be authorized to use cannabis, be it in its dry herbal form or in its myriad derivatives such as waxes, oils, or medicated food products.
The measure removes a number of burdens related to the state’s medical marijuana program, including requirements that applicants must be fingerprinted and have their criminal backgrounds screened.
Patients will be required to receive an Illinois Cannabis Tracking System certification from their doctors, upon which they can register online for a 90-day medical cannabis license that costs $10 and allows access to a maximum of 2.5 ounces every two weeks.
Upon signing the bill last August, Governor Bruce Rauner cited the massive scale of the narcotics problem in the state along with the proven health benefits of cannabis as reason for passing the law. The governor said:
“We’ve got to do everything we can to stop this vicious epidemic … We are creating an alternative to opioid addiction. … It’s clear that medical marijuana treats pain effectively, and is less addictive and disruptive than opioids.”
In recent years, drug overdose deaths have reached monstrous proportions, with 65,000 fatal drug overdoses taking place in 2017 alone. In 2016, almost 2,000 people in Illinois died from narcotics overdoses – an 82 percent increase since 2013.
Many who abuse the pills have prolonged addictive fixations on opioids, with the hardest-hit age group ranging from 25 to 34 years old. Out of that age group, 12,325 died in 2017, among whom two-thirds were men.
The program comes as data from various studies attest to the medical and health benefits of cannabis as a credible alternative to pharmaceutical drugs.
It also comes as recent court filings from a major lawsuit by the Massachusetts attorney general against Purdue Pharma, the company responsible for making the OxyContin narcotic pill, reveal how Big Pharma executives deliberately misled doctors and patients about the dangerous and addictive nature of the opioid in hopes of maximizing company profits.
Chris Stone, the owner of Illinois medical cannabis dispensary HCI Alternatives, told local news station WQAD 8 that he hopes authorities track the positive results that he’s sure will result from the program.
“Hopefully as they take statistics on this and they see this program over the first twelve months, be able to do the data mining and the research and the surveying to hopefully see those deaths go down and the additional cases go down,” he said.
In 1996, California became the first state to legalize cannabis for medical use, and more than 30 states have since done the same.
Illinois followed suit in 2013 with the Compassionate Use of Medicinal Cannabis Pilot Program with 34,000 people having been approved for the program as of 2018.
Ten states along with Washington, D.C. have freed the herb almost entirely, allowing adults over 21 to partake in the recreational use of marijuana. However, cannabis remains illegal under U.S. federal law.
Thanks to: https://themindunleashed.com
The New York Department of Health has amended the state’s medical marijuana program to include opioid prescription replacement and painkiller abuse as qualifying conditions to access legal weed. In an effort to combat the nation’s opioid abuse epidemic and provide citizens with non-addictive tools to fight chronic pain, the New York Department Of Health has amended the Empire State’s medical marijuana program to include opioid prescription replacement and painkiller abuse as qualifying conditions to access legal weed. The new rules, effective immediately, were added as emergency regulations, pushed forward by New York Health Commissioner Dr. Howard Zucker. The anti-opioid measures were first introduced last month, and traditional bureaucratic practices would have delayed implementation until August. Bypassing those expected channels, the Department of Health intends to enact the policy change as soon as possible. “Medical marijuana has been shown to be an effective treatment for pain that may also reduce the chance of opioid dependence,” Dr. Zucker detailed in a press release announcing the emergency regulations. “Adding opioid replacement as a qualifying condition for medical marijuana offers providers another treatment option, which is a critical step in combating the deadly opioid epidemic affecting people across the state.” New York first opened its medical marijuana program in 2016, with 12 qualifying conditions allowing cancer patients, Alzheimer’s sufferers, and more to purchase cannabis pills, tinctures, and vaporizers through state-licensed dispensaries. In the years since, Empire State lawmakers and advocates have pushed to expand the program, with a number of high-profile politicians now pushing to legalize the plant for recreational use, too.
In the meantime, though, the addition of opioid-related qualifying conditions will theoretically open access to medical cannabis to thousands upon thousands of New Yorkers. According to the [url=https://regs.health.ny.gov/sites/default/files/pdf/emergency_regulations/Medical Use of Marihuana_3.pdf]Department of Health’s emergency regulations[/url], “registered practitioners may certify patients to use medical marijuana as a replacement for opioids, provided that the precise underlying condition for which an opioid would otherwise be prescribed is stated on the patient’s certification. In addition, the regulation adds opioid use disorder as an associated condition. This allows patients with opioid use disorder who are enrolled in a certified treatment program to use medical marijuana as an opioid replacement.” While scientific research has time-and-again found cannabis to be a near-miraculous replacement for opioid painkillers — not only in the treatment of pain, but in addiction rehabilitation — most medical marijuana programs across the country have stopped short of condoning weed as a direct replacement for pills. A similar bill that would have allowed Colorado doctors to replace opioid prescriptions with cannabis recommendations was shot down in the state legislature earlier this year. And another bill in Illinois that would turn any valid opioid prescription into a de facto MMJ recommendation has been sitting on the desk of Governor Bruce Rauner for months. New York’s amended medical marijuana rules will become official at the end of the month, on August 1st, where they will then be subject to a 60-day public comment period. Source: https://merryjane.com
Thanks to: http://cbdhealthcures.com
Cannabis and Arthritis By Jeremy Kossen — 3/28/2016 📷 It’s no secret: America’s baby boomers are aging, and one of the most common ailments in older populations is arthritis. According to the U.S. Center for Disease Control and Prevention(CDC), 53 million Americans have arthritis, with women making up 60 percent of the arthritis diagnoses. But what exactly is arthritis, and how can cannabis help it? What is Arthritis?“Arthritis” is an umbrella term used to describe 200 rheumatic diseases affecting the joints and their surrounding tissues. It causes inflammation and stiffness that develops abruptly or gradually around one or more joints. Causes and Forms of ArthritisAlthough more common in seniors, arthritis can severely impair a person of any age, leaving him or her unable to work or perform daily duties. In the United States, arthritis is the most common cause of disability, and high levels of stress and depression are often associated. Genetics may cause arthritis, along with obesity, joint damage, infections, and occupations requiring repetitive bending or squatting. Dysfunction of the immune system and an abnormal metabolism can also lead to various forms of arthritis, though many rheumatoid diseases are caused by a combination of factors. Forms of arthritis are broken into seven main categories:
Arthritis Treatment MethodsAlthough they don’t heal joint inflammation, analgesics like Tylenol, Percocet, and Vicodin may be prescribed to reduce pain along with creams containing menthol or capsaicin. Over-the-counter non-steroidal anti-inflammatory drugs (NSAIDs) like Advil, Motrin, or Aleve may be taken to reduce pain and inflammation. Rheumatoid arthritis is treated with disease-modifying anti-rheumatic drugs (DMARDs) to prevent the immune system from attacking inflamed joints. Corticosteroids like prednisone and cortisone may also be prescribed to reduce inflammation and suppress the immune system. Exercise can ease pain and stress levels for people with arthritis, but nearly a quarter of adults diagnosed with arthritis report being physically inactive. Dietary changes may manage arthritis, as meats and foods high in sugar can exacerbate inflammation. How Cannabis Can Help ArthritisWhile cannabis is classified as a Schedule I drug by the federal government, meaning it’s considered highly addictive with no medical value and research on it is severely restricted — a scientific consensus has nevertheless emerged on its therapeutic value based on a growing body of successful preclinical and clinical trials. To the delight of many, those studies show that cannabis has anti-inflammatory effects that can help arthritis patients live happier, healthier lives. Consequently, cannabis is gaining popularity as a treatment for arthritis. Cannabis can ease pain and reduce swelling without the potentially life-threatening side effects caused by frequent NSAID or opiate use. In the summer of 2015, the Canadian Arthritis Society funded a three-year research grant to a Dalhousie University researcher to determine if marijuana can relieve pain or repair arthritic joints. Pain-detecting nerves are filled with cannabinoid receptors, and according to researcher Jason McDougall, cannabinoids control the firing of pain signals from the joint to the brain by sticking themselves to nerve receptors. Another controlled study, conducted by the Royal National Hospital for Rheumatic Disease in the UK, showed that cannabinoids provided statistically significant improvements in pain on movement, pain at rest, and quality of sleep. At a time when opiate abuse has reached epidemic proportions, cannabis treatment can be a far less harmful and less addictive way to treat those suffering from chronic pain associated with arthritis. According to Mike Hart, MD, head physician of the Ontario Chapter at Marijuana for Trauma (MFT):
“Cannabis is much more effective and safer long term solution than opioids. The science is clear and demonstrates that cannabis is far safer than opioids. In fact, it’s not even close. Opioids have killed more people than all illegal drugs combined, while cannabis has never killed a single person.”
Not only is cannabis an effective alternative treatment to NSAIDs or opiates, it can help people get off dangerous drugs such as opioids. According to Dr. Hart, “I have literally helped hundreds of patients reduce or eliminate their dependence on opioids.” In addition to increasing numbers of professionals within the medical industry recognizing the therapeutic value of cannabis, the public has also become more receptive to medical marijuana treatment. In January 2014, CBS News conducted a national poll finding that 86 percent of Americans believe doctors should be permitted to prescribe cannabis to patients who suffer from serious illnesses such as arthritis. As far back as 2004, the American Association of Retired Persons (AARP), which boasts 35 million members, published a national poll revealing that 72 percent of seniors support allowing the use of doctor-recommended cannabis to treat patients. Do you use medical marijuana to help manage your arthritis symptoms? If so, which strains have you found help best? Share your recommendations in the comments! Thanks to: https://nurse194666.wordpress.com http://www.oom2.com/t37709-cannabis-and-arthritis
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